TCHP Antibody

Product Specifications

Background

TCHP may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. This protein may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.

NCBI Gene ID

84260

Swiss Prot

Q9BT92

Accession Number

Q9BT92

Host

Rabbit

Reactivity

Human

Immunogen

This TCHP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the Central region of human TCHP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Symbol

TCHP

NCBI Official Name

Trichoplein keratin filament-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Vecchione, A. Oncogene 28 (2), 257-269 (2009)

Background Reference 02

Tokumasu, F. J. Cell. Sci. 118 (PT 5), 1091-1098 (2005)

Background Reference 03

Nishizawa, M. J. Cell. Sci. 118 (PT 5), 1081-1090 (2005)

Other Product Names

Trichoplein keratin filament-binding protein, Protein TCHP, Mitochondrial protein with oncostatic activity, Mitostatin, Tumor suppressor protein, TCHP {ECO:0000312|EMBL:AAH042851}