CD49f Antibody

Product Specifications

Background

The CD49f protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

NCBI Gene ID

3655

Swiss Prot

P23229

Accession Number

P23229

Host

Rabbit

Reactivity

Human

Immunogen

This CD49f antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1082-1110 amino acids from the C-terminal region of human CD49f.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

127 kDa

Fragment

Rabbit Ig

Symbol

ITGA6

NCBI Official Name

Integrin alpha-6

NCBI Organism

Homo sapiens

Background Reference 01

Kim, T.H., et.al., Mol. Cancer Res. (10), 1605-1612 (2009)

Background Reference 02

Eeles, R.A., et.a.l, Nat. Genet. 41 (10), 1116-1121 (2009)

Other Product Names

Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, Integrin alpha-6 heavy chain, Integrin alpha-6 light chain, Processed integrin alpha-6, Alpha6p, ITGA6