EXTL2 Antibody

Product Specifications

Background

EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

NCBI Gene ID

2135

Swiss Prot

Q9UBQ6

Accession Number

Q9UBQ6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EXTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-295 amino acids from the C-terminal region of human EXTL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

EXTL2

NCBI Official Name

Exostosin-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Kaidonis, X., et.al, Eur. J. Hum. Genet. 18 (2), 194-199 (2010)

Background Reference 02

Sobhany, M., et.al, J. Biol. Chem. 280 (25), 23441-23445 (2005)

Other Product Names

Exostosin-like 2, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, Alpha-GalNAcT EXTL2, EXT-related protein 2, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Processed exostosin-like 2, EXTL2, EXTR2