MPP6 Antibody
Product Specifications
Background
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily.
NCBI Gene ID
51678
Swiss Prot
Q9NZW5
Accession Number
Q9NZW5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MPP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human MPP6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
MPP6
NCBI Official Name
MAGUK p55 subfamily member 6
NCBI Organism
Homo sapiens
Background Reference 01
Scheel, A.K., et.al., Ann. Rheum. Dis. 65 (5), 595-600 (2006)
Background Reference 02
Rush, J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)
Background Reference 03
Rush, J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)
Other Product Names
MAGUK p55 subfamily member 6, Veli-associated MAGUK 1, VAM-1, MPP6, VAM1
Tested Applications
WB, Flow
Protein ID
42560556
Physical Properties
Liquid
Curated Selection
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