MTTP Antibody
Product Specifications
Background
MTTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a entral role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
NCBI Gene ID
4547
Swiss Prot
P55157
Accession Number
P55157
Host
Rabbit
Reactivity
Human
Immunogen
This MTTP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-842 amino acids from the C-terminal region of human MTTP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
99 kDa
Fragment
Rabbit Ig
Symbol
MTTP
NCBI Official Name
Microsomal triglyceride transfer protein large subunit
NCBI Organism
Homo sapiens
Background Reference 01
Dai, K., et.al., Arterioscler. Thromb. Vasc. Biol. 30 (3), 568-574 (2010)
Background Reference 02
Oliveira, C.P., et.al., J. Gastroenterol. Hepatol. 25 (2), 357-361 (2010)
Other Product Names
Microsomal triglyceride transfer protein large subunit, MTTP, MTP
Tested Applications
WB, IHC-P
Protein ID
1709167
Physical Properties
Liquid
Curated Selection
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