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MTTP Antibody

Product Specifications

Background

MTTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a entral role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

NCBI Gene ID

4547

Swiss Prot

P55157

Accession Number

P55157

Host

Rabbit

Reactivity

Human

Immunogen

This MTTP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-842 amino acids from the C-terminal region of human MTTP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

99 kDa

Fragment

Rabbit Ig

Symbol

MTTP

NCBI Official Name

Microsomal triglyceride transfer protein large subunit

NCBI Organism

Homo sapiens

Background Reference 01

Dai, K., et.al., Arterioscler. Thromb. Vasc. Biol. 30 (3), 568-574 (2010)

Background Reference 02

Oliveira, C.P., et.al., J. Gastroenterol. Hepatol. 25 (2), 357-361 (2010)

Other Product Names

Microsomal triglyceride transfer protein large subunit, MTTP, MTP

Tested Applications

WB, IHC-P

Protein ID

1709167

Physical Properties

Liquid

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