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CDIPT Antibody

Product Specifications

Background

CDIPT is a protein which is phosphatidylinositol breakdown products that are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus.

NCBI Gene ID

10423

Swiss Prot

O14735

Accession Number

O14735

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CDIPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human CDIPT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Symbol

CDIPT

NCBI Official Name

CDP-diacylglycerol--inositol 3-phosphatidyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

De Serres, F.J., et.al., Monaldi Arch Chest Dis 63 (3), 133-141 (2005)

Background Reference 02

Lykidis, A., et.al., J. Biol. Chem. 272 (52), 33402-33409 (1997)

Other Product Names

CDP-diacylglycerol--inositol 3-phosphatidyltransferase, Phosphatidylinositol synthase, PI synthase, PtdIns synthase, CDIPT, PIS, PIS1

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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