CDC37 Antibody
Product Specifications
Background
CDC37 is a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
NCBI Gene ID
11140
Swiss Prot
Q16543
Accession Number
Q16543
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This CDC37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human CDC37.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Symbol
CDC37
NCBI Official Name
Hsp90 co-chaperone Cdc37
NCBI Organism
Homo sapiens
Background Reference 01
Dai, K., et.al., J. Biol. Chem. 271 (36), 22030-22034 (1996)
Background Reference 02
Lamphere, L., et.al., Oncogene 14 (16), 1999-2004 (1997)
Other Product Names
Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37, Hsp90 co-chaperone Cdc37, N-terminally processed, CDC37, CDC37A
Tested Applications
WB, IHC-P, Flow
Protein ID
21542000
Physical Properties
Liquid
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