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COTL1 Antibody

Product Specifications

Background

COTL1 is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis.

NCBI Gene ID

23406

Swiss Prot

Q14019

Accession Number

Q14019

Host

Rabbit

Reactivity

Human

Immunogen

This COTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-142 amino acids from the C-terminal region of human COTL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

COTL1

NCBI Official Name

Coactosin-like protein

NCBI Organism

Homo sapiens

Background Reference 01

Provost, P., et.al., Proc. Natl. Acad. Sci. U.S.A. 96 (5), 1881-1885 (1999)

Background Reference 02

Provost, P., et.al., J. Biol. Chem. 276 (19), 16520-16527 (2001)

Other Product Names

Coactosin-like protein, COTL1, CLP

Tested Applications

WB, IHC-P, Flow

Protein ID

21759076

Physical Properties

Liquid

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