PARD3 Antibody

Product Specifications

Background

PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048) -interactive binding (CRIB) domain.

NCBI Gene ID

56288

Swiss Prot

Q8TEW0

Accession Number

Q8TEW0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PARD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1329-1356 amino acids from the C-terminal region of human PARD3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

151 kDa

Fragment

Rabbit Ig

Symbol

PARD3

NCBI Official Name

Partitioning defective 3 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Noda, Y., et.al., Genes Cells (2), 107-119 (2001)

Background Reference 02

Beausoleil, S.A., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)

Other Product Names

Partitioning defective 3 homolog, PAR-3, PARD-3, Atypical PKC isotype-specific-interacting protein, ASIP, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3, PAR3A