IGFBP2 Antibody

Product Specifications

Background

IGFBP2-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

NCBI Gene ID

3485

Swiss Prot

P18065

Accession Number

P18065

Host

Rabbit

Reactivity

Human

Immunogen

This IGFBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human IGFBP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

IGFBP2

NCBI Official Name

Insulin-like growth factor-binding protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Arafat, A.M., et.al., J. Clin. Endocrinol. Metab. 94 (12), 5093-5101 (2009)

Background Reference 02

Yazawa, T., et.al., Am. J. Pathol. 175 (3), 976-987 (2009)

Other Product Names

Insulin-like growth factor-binding protein 2, IBP-2, IGF-binding protein 2, IGFBP-2, IGFBP2, BP2, IBP2

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

290457647

Physical Properties

Liquid

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