PRKCA Antibody
Product Specifications
Background
PRKCA is a calcium-activated, phospholipid-dependent, serine-and threonine-specific enzyme. It may play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
NCBI Gene ID
5578
Swiss Prot
P17252
Accession Number
P17252
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PRKCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human PRKCA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Symbol
PRKCA
NCBI Official Name
Protein kinase C alpha type
NCBI Organism
Homo sapiens
Background Reference 01
Gysin, S. and Imber, R. et.al., Eur. J. Biochem. 240 (3), 747-750 (1996) Rider, M.H., et.al., Biochem. J. 285 (PT 2), 405-411 (1992)
Other Product Names
Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
317373571
Physical Properties
Liquid
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