PP2A alpha Antibody

Product Specifications

Background

PPP2CA/B represents the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.

NCBI Gene ID

5515

Swiss Prot

P67775

Accession Number

P67775

Host

Rabbit

Reactivity

Human

Immunogen

This PP2A alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-304 amino acids from the C-terminal region of human PP2A alpha.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rabbit, Rat, Drosophila

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

PPP2CA

NCBI Official Name

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

NCBI Organism

Homo sapiens

Background Reference 01

Gergs, U., et al., J. Biol. Chem. 279 (39) :40827-40834 (2004) .

Background Reference 02

Prickett, T.D., et al., J. Biol. Chem. 279 (37) :38912-38920 (2004) .

Background Reference 03

Scott, G.K., et al., EMBO J. 22 (23) :6234-6244 (2003) .

Background Reference 04

Rao, R.K., et al., Biochem. Biophys. Res. Commun. 293 (1) :610-616 (2002) .

Other Product Names

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA

Tested Applications

WB, IHC-P

Protein ID

54038809

Physical Properties

Liquid

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