MEG2 Antibody
Product Specifications
Background
MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
NCBI Gene ID
5780
Swiss Prot
P43378
Accession Number
P43378
Host
Rabbit
Reactivity
Human
Immunogen
This MEG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MEG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Symbol
PTPN9
NCBI Official Name
Tyrosine-protein phosphatase non-receptor type 9
NCBI Organism
Homo sapiens
Background Reference 01
Kruger, J.M., et al., J. Biol. Chem. 277 (4) :2620-2628 (2002) .
Background Reference 02
Qi, Y., et al., J. Cell. Biochem. 86 (1) :79-89 (2002) .
Background Reference 03
Gu, M., et al., Proc. Natl. Acad. Sci. U.S.A. 89 (7) :2980-2984 (1992) .
Other Product Names
Tyrosine-protein phosphatase non-receptor type 9, Protein-tyrosine phosphatase MEG2, PTPase MEG2, PTPN9
Tested Applications
WB, IHC-P
Protein ID
1172724
Physical Properties
Liquid
Curated Selection
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