PI3KR2 Antibody

Product Specifications

Background

PI3KR2 binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.

NCBI Gene ID

5296

Swiss Prot

O00459

Accession Number

O00459

Host

Rabbit

Reactivity

Human

Immunogen

This PI3KR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-298 amino acids from the C-terminal region of human PI3KR2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

82 kDa

Fragment

Rabbit Ig

Symbol

PIK3R2

NCBI Official Name

Phosphatidylinositol 3-kinase regulatory subunit beta

NCBI Organism

Homo sapiens

Background Reference 01

Janssen, J.W., et al., Oncogene 16 (13) :1767-1772 (1998) .

Background Reference 02

Volinia, S., et al., Oncogene 7 (4) :789-793 (1992) .

Background Reference 03

Carpenter, C.L., et al., J. Biol. Chem. 265 (32) :19704-19711 (1990) .

Other Product Names

Phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase subunit p85-beta, PtdIns-3-kinase regulatory subunit p85-beta, PIK3R2