PIM2 Antibody
Product Specifications
Background
Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
NCBI Gene ID
11040
Swiss Prot
Q9P1W9
Accession Number
Q9P1W9
Host
Rabbit
Reactivity
Human
Immunogen
This PIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Symbol
PIM2
NCBI Official Name
Serine/threonine-protein kinase pim-2
NCBI Organism
Homo sapiens
Background Reference 01
Yan, B., et al., J. Biol. Chem. 278 (46) :45358-45367 (2003) .
Background Reference 02
Baytel, D., et al., Biochim. Biophys. Acta 1442 (2-3), 274-285 (1998) .
Other Product Names
Serine/threonine-protein kinase pim-2, Pim-2h, PIM2
Tested Applications
WB, IHC-P, IP
Protein ID
20139243
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
E0010-01D 100 µg
E2F1 Transcription Factor (E2F 1, Retinoblastoma associated protein 1, Retinoblastoma binding protein 3, PBR3, RBAP-1, RBBP3, RBP3)
Ask
View Details 