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MLK2 Antibody

Product Specifications

Background

MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

NCBI Gene ID

4294

Swiss Prot

Q02779

Accession Number

Q02779

Host

Rabbit

Reactivity

Human

Immunogen

This MLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 628-659 amino acids from the C-terminal region of human MLK2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-288

Calculated Molecular Weight

104 kDa

Fragment

Rabbit Ig

Symbol

MAP3K10

NCBI Official Name

Mitogen-activated protein kinase kinase kinase 10

NCBI Organism

Homo sapiens

Background Reference 01

Dorow, D.S., et al., Eur. J. Biochem. 234 (2) :492-500 (1995) .

Background Reference 02

Katoh, M., et al., Oncogene 10 (7) :1447-1451 (1995) .

Background Reference 03

Dorow, D.S., et al., Eur. J. Biochem. 213 (2) :701-710 (1993) .

Other Product Names

Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST, MAP3K10, MLK2, MST

Tested Applications

WB, IHC-P

Protein ID

145559494

Physical Properties

Liquid

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