MAP2K5 Antibody

Product Specifications

Background

MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.

NCBI Gene ID

5607

Swiss Prot

Q13163

Accession Number

Q13163

Host

Rabbit

Reactivity

Human

Immunogen

This MAP2K5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from human MAP2K5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Symbol

MAP2K5

NCBI Official Name

Dual specificity mitogen-activated protein kinase kinase 5

NCBI Organism

Homo sapiens

Background Reference 01

Raviv, Z., J. Cell. Sci. 117 (PT 9), 1773-1784 (2004)

Background Reference 02

Kato, Y., EMBO J. 16 (23), 7054-7066 (1997)

Background Reference 03

English, J.M., J. Biol. Chem. 274 (44), 31588-31592 (1999)

Other Product Names

Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5

Tested Applications

WB, IHC-P

Protein ID

118572669

Physical Properties

Liquid

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