CDC25C Antibody
Product Specifications
Background
CDC25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest.
NCBI Gene ID
995
Swiss Prot
P30307
Accession Number
P30307
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CDC25C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-142 amino acids from the Central region of human CDC25C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDC25C
NCBI Official Name
M-phase inducer phosphatase 3
NCBI Organism
Homo sapiens
Background Reference 01
Varmeh, S., Mol. Cancer Ther. (12), 3789-3799 (2008)
Background Reference 02
Long, J.M., Cell Cycle (19), 3062-3073 (2008)
Background Reference 03
Bonnet, J., Cell Cycle (13), 1991-1998 (2008)
Other Product Names
M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C
Tested Applications
WB
Protein ID
116242631
Physical Properties
Liquid
Curated Selection
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