MUC20 Antibody
Product Specifications
Background
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
200958
Swiss Prot
Q8N307
Accession Number
Q8N307
Host
Rabbit
Reactivity
Human
Immunogen
This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human MUC20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Symbol
MUC20
NCBI Official Name
Mucin-20
NCBI Organism
Homo sapiens
Background Reference 01
Li, G., Am. J. Nephrol. 26 (1), 43-49 (2006)
Background Reference 02
Suzuki, Y., Genome Res. 14 (9), 1711-1718 (2004)
Background Reference 03
Higuchi, T., Mol. Cell. Biol. 24 (17), 7456-7468 (2004)
Background Reference 04
Higuchi, T., J. Biol. Chem. 279 (3), 1968-1979 (2004)
Other Product Names
Mucin-20, MUC-20, MUC20, KIAA1359
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
317373415
Physical Properties
Liquid
Curated Selection
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