PR48 Antibody
Product Specifications
Background
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. This protein belongs to the B'' family. The B'' family has been further divided into subfamilies. This protein belongs to the beta subfamily of regulatory subunit B''.
NCBI Gene ID
10272501628227
Swiss Prot
Q9Y5P8
Accession Number
Q9Y5P8
Host
Rabbit
Reactivity
Human
Immunogen
This PR48 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human PR48.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-195
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP2R3B
NCBI Official Name
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Stevens, I., Eur. J. Biochem. 270 (2), 376-387 (2003)
Background Reference 02
Yokoyama, N., Oncogene 20 (42), 6057-6065 (2001)
Background Reference 03
Yan, Z., Mol. Cell. Biol. 20 (3), 1021-1029 (2000)
Other Product Names
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta, PP2A subunit B isoform PR48, Protein phosphatase 2A 48 kDa regulatory subunit, PPP2R3B, PPP2R3L
Tested Applications
WB
Protein ID
158523346
Physical Properties
Liquid
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