KIT Antibody

Product Specifications

Background

KIT is the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) .

NCBI Gene ID

3815

Swiss Prot

P10721

Accession Number

P10721

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 680-711 amino acids from human KIT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

110 kDa

Fragment

Rabbit Ig

Symbol

KIT

NCBI Official Name

Mast/stem cell growth factor receptor Kit

NCBI Organism

Homo sapiens

Background Reference 01

Wardelmann, E., et al., Int. J. Cancer 106 (6) :887-895 (2003) .

Background Reference 02

Lennartsson, J., et al., Exp. Cell Res. 288 (1) :110-118 (2003) .

Background Reference 03

Sakuma, Y., et al., Cancer Sci 94 (6) :486-491 (2003) .

Background Reference 04

Araki, K., et al., Lung Cancer 40 (2) :173-180 (2003) .

Other Product Names

Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR