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CA3 Antibody

Product Specifications

Background

Carbonic anhydrase III (CAIII) is a member of carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

NCBI Gene ID

761

Swiss Prot

P07451

Accession Number

P07451

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human CA3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CA3

NCBI Official Name

Carbonic anhydrase 3

NCBI Organism

Homo sapiens

Background Reference 01

Du, A.L., Autoimmunity 42 (3), 209-215 (2009)

Background Reference 02

Dai, H.Y., Mol. Carcinog. 47 (12), 956-963 (2008)

Background Reference 03

Gailly, P., Kidney Int. 74 (1), 52-61 (2008)

Other Product Names

Carbonic anhydrase 3, Carbonate dehydratase III, Carbonic anhydrase III, CA-III, CA3

Tested Applications

WB

Protein ID

134047703

Physical Properties

Liquid

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