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PPBP Antibody

Product Specifications

Background

PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

NCBI Gene ID

5473

Swiss Prot

P02775

Accession Number

P02775

Host

Rabbit

Reactivity

Human

Immunogen

This PPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human PPBP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

14 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPBP

NCBI Official Name

Platelet basic protein

NCBI Organism

Homo sapiens

Background Reference 01

Majumdar S., J. Biol. Chem. 266:5785-5789 (1991)

Background Reference 02

Zhang C., Blood 98:610-617 (2001)

Background Reference 03

Aivado, M., Proc. Natl. Acad. Sci. U.S.A. 104 (4), 1307-1312 (2007)

Other Product Names

Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, TC-2, Connective tissue-activating peptide III (1-81), CTAP-III (1-81), Beta-thromboglobulin, Beta-TG, Neutrophil-activating peptide 2 (74), NAP-2 (74), Neutrophil-activating peptide 2 (73), NAP-2 (73), Neutrophil-activating peptide 2, NAP-2, TC-1, Neutrophil-activating peptide 2 (1-66), NAP-2 (1-66), Neutrophil-activating peptide 2 (1-63), NAP-2 (1-63), PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1

Tested Applications

WB

Protein ID

129874

Physical Properties

Liquid

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