GIT1 Antibody

Product Specifications

Background

GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.

NCBI Gene ID

28964

Swiss Prot

Q9Y2X7

Accession Number

Q9Y2X7

Host

Rabbit

Reactivity

Human

Immunogen

This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

GIT1

NCBI Official Name

ARF GTPase-activating protein GIT1

NCBI Organism

Homo sapiens

Background Reference 01

Sato, H., Biochem. Biophys. Res. Commun. 368 (1), 157-161 (2008)

Background Reference 02

Jones, N.P., Mol. Cell. Biol. 27 (16), 5790-5805 (2007)

Background Reference 03

Schmalzigaug, R., Cell. Signal. 19 (8), 1733-1744 (2007)

Background Reference 04

Stockton, R., Mol. Biol. Cell 18 (6), 2346-2355 (2007)

Other Product Names

ARF GTPase-activating protein GIT1, ARF GAP GIT1, Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1, GIT1