BCOR Antibody
Product Specifications
Background
BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
NCBI Gene ID
54880
Swiss Prot
Q6W2J9
Accession Number
Q6W2J9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1137 amino acids from the Central region of human BCOR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
192 kDa
Fragment
Rabbit Ig
Symbol
BCOR
NCBI Official Name
BCL-6 corepressor
NCBI Organism
Homo sapiens
Background Reference 01
Ghetu, A.F., Mol. Cell 29 (3), 384-391 (2008)
Background Reference 02
Hilton, E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)
Other Product Names
BCL-6 corepressor, BCoR, BCOR, KIAA1575
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Curated Selection
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