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BCOR Antibody

Product Specifications

Background

BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.

NCBI Gene ID

54880

Swiss Prot

Q6W2J9

Accession Number

Q6W2J9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1137 amino acids from the Central region of human BCOR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

192 kDa

Fragment

Rabbit Ig

Symbol

BCOR

NCBI Official Name

BCL-6 corepressor

NCBI Organism

Homo sapiens

Background Reference 01

Ghetu, A.F., Mol. Cell 29 (3), 384-391 (2008)

Background Reference 02

Hilton, E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)

Other Product Names

BCL-6 corepressor, BCoR, BCOR, KIAA1575

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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