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CA5B Antibody

Product Specifications

Background

CA5B belongs a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. This protein is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. The protein has a wider tissue distribution than CA VA, which is restricted to the liver.

NCBI Gene ID

11238

Swiss Prot

Q9Y2D0

Accession Number

Q9Y2D0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CA5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-283 amino acids from the C-terminal region of human CA5B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

CA5B

NCBI Official Name

Carbonic anhydrase 5B, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Vullo, D., Nishimori, I. Bioorg. Med. Chem. Lett. 17 (5), 1336-1340 (2007)

Background Reference 02

Shah, G.N. Proc. Natl. Acad. Sci. U.S.A. 97 (4), 1677-1682 (2000)

Background Reference 03

Fujikawa-Adachi, K. J. Biol. Chem. 274 (30), 21228-21233 (1999)

Other Product Names

Carbonic anhydrase 5B, mitochondrial, Carbonate dehydratase VB, Carbonic anhydrase VB, CA-VB, CA5B

Tested Applications

WB, IHC-P, Flow

Protein ID

8928041

Physical Properties

Liquid

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