Cyclin A Antibody
Product Specifications
Background
CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
NCBI Gene ID
890
Swiss Prot
P20248
Accession Number
P20248
Host
Rabbit
Reactivity
Human
Immunogen
This Cyclin A (CCNA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-84 amino acids from the N-terminal region of human Cyclin A (CCNA2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-797
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Symbol
CCNA2
NCBI Official Name
Cyclin-A2
NCBI Organism
Homo sapiens
Background Reference 01
Henglein B., Proc. Natl. Acad. Sci. U.S.A. 91:5490-5494 (1994)
Background Reference 02
Wang J., Nature 343:555-557 (1990)
Background Reference 03
Tsang, W.Y., J. Cell Biol. 178 (4), 621-633 (2007)
Other Product Names
Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA
Tested Applications
WB, IHC-P, Flow
Protein ID
311033358
Physical Properties
Liquid
Curated Selection
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