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CAMK2A Antibody

Product Specifications

Background

CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.

NCBI Gene ID

815

Swiss Prot

Q9UQM7

Accession Number

Q9UQM7

Host

Rabbit

Reactivity

Human

Immunogen

This CAMK2A (CAMK2 alpha) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-478 amino acids from the C-terminal region of human CAMK2A (CAMK2 alpha) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

CAMK2A

NCBI Official Name

Calcium/calmodulin-dependent protein kinase type II subunit alpha

NCBI Organism

Homo sapiens

Background Reference 01

Blume-Jensen P, et al. Nature 2001. 411: 355.

Background Reference 02

Cantrell D, J. Cell Sci. 2001. 114: 1439.

Background Reference 03

JhiangOncogene 2000. 19: 5590.

Background Reference 04

Manning G, et al. Science 2002. 298: 1912.

Other Product Names

Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968

Tested Applications

WB, IHC-P

Protein ID

296434552

Physical Properties

Liquid

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