MNK2 Antibody

Product Specifications

Background

MKNK2 may play a role in the response to environmental stress and cytokines. This protein appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

NCBI Gene ID

2872

Swiss Prot

Q9HBH9

Accession Number

Q9HBH9

Host

Rabbit

Reactivity

Human

Immunogen

This MNK2 (MKNK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-432 amino acids from the C-terminal region of human MNK2 (MKNK2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MKNK2

NCBI Official Name

MAP kinase-interacting serine/threonine-protein kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Scheper, G.C., et al., Mol. Cell. Biol. 23 (16) :5692-5705 (2003) . Knauf, U., et al., Mol. Cell. Biol. 21 (16) :5500-5511 (2001) . Scheper, G.C., et al., Mol. Cell. Biol. 21 (3) :743-754 (2001) . Slentz-Kesler, K., et al., Genomics 69 (1) :63-71 (2000) . Haribabu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 90 (20) :9398-9402 (1993) .

Other Product Names

MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2, MKNK2, GPRK7, MNK2