CBS Antibody
Product Specifications
Background
CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
NCBI Gene ID
102724560875
Swiss Prot
P35520
Accession Number
P35520
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
CBS
NCBI Official Name
Cystathionine beta-synthase
NCBI Organism
Homo sapiens
Background Reference 01
Ravel, C., et.al., PLoS ONE (8), E6540 (2009)
Other Product Names
Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase, CBS
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
543959
Physical Properties
Liquid
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