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OTC Antibody

Product Specifications

Background

OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia.

NCBI Gene ID

5009

Swiss Prot

P00480

Accession Number

P00480

Host

Rabbit

Reactivity

Human

Immunogen

This OTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human OTC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Symbol

OTC

NCBI Official Name

Ornithine carbamoyltransferase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Hansmannel, F., et.al., Neurosci. Lett. 449 (1), 76-80 (2009)

Other Product Names

Ornithine carbamoyltransferase, mitochondrial, Ornithine transcarbamylase, OTCase, OTC

Tested Applications

WB, IHC-P, Flow

Protein ID

84028235

Physical Properties

Liquid

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