HMGCS2 Antibody
Product Specifications
Background
HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.
NCBI Gene ID
3158
Swiss Prot
P54868
Accession Number
P54868
Host
Rabbit
Reactivity
Human
Immunogen
This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
HMGCS2
NCBI Official Name
Hydroxymethylglutaryl-CoA synthase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Lu, Y., et.al., J. Lipid Res. 49 (12), 2582-2589 (2008)
Other Product Names
Hydroxymethylglutaryl-CoA synthase, mitochondrial, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, HMGCS2
Tested Applications
WB, IHC-P, Flow
Protein ID
1708234
Physical Properties
Liquid
Curated Selection
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