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BGN Antibody

Product Specifications

Background

BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival.

NCBI Gene ID

633

Swiss Prot

P21810

Accession Number

P21810

Host

Rabbit

Reactivity

Human

Immunogen

This BGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of human BGN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

BGN

NCBI Official Name

Biglycan

NCBI Organism

Homo sapiens

Background Reference 01

Sardo, M.A., Clin. Chim. Acta 406 (1-2), 89-93 (2009)

Background Reference 02

Hwang, J.Y., Am. J. Pathol. 173 (6), 1919-1928 (2008)

Background Reference 03

Traupe, H., Genomics 13 (2), 481-483 (1992)

Other Product Names

Biglycan, Bone/cartilage proteoglycan I, PG-S1, BGN, SLRR1A

Tested Applications

WB, IHC-P, Flow

Protein ID

266762

Physical Properties

Liquid

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