BGN Antibody
Product Specifications
Background
BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival.
NCBI Gene ID
633
Swiss Prot
P21810
Accession Number
P21810
Host
Rabbit
Reactivity
Human
Immunogen
This BGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of human BGN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
BGN
NCBI Official Name
Biglycan
NCBI Organism
Homo sapiens
Background Reference 01
Sardo, M.A., Clin. Chim. Acta 406 (1-2), 89-93 (2009)
Background Reference 02
Hwang, J.Y., Am. J. Pathol. 173 (6), 1919-1928 (2008)
Background Reference 03
Traupe, H., Genomics 13 (2), 481-483 (1992)
Other Product Names
Biglycan, Bone/cartilage proteoglycan I, PG-S1, BGN, SLRR1A
Tested Applications
WB, IHC-P, Flow
Protein ID
266762
Physical Properties
Liquid
Curated Selection
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