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MAPE Antibody

Product Specifications

Background

MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.

NCBI Gene ID

23532

Swiss Prot

P78395

Accession Number

P78395

Host

Rabbit

Reactivity

Human

Immunogen

This MAPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-428

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Symbol

PRAME

NCBI Official Name

Melanoma antigen preferentially expressed in tumors

NCBI Organism

Homo sapiens

Background Reference 01

Rezvani, K., Blood 113 (10), 2245-2255 (2009)

Background Reference 02

Qin, Y., Leuk. Res. 33 (3), 384-390 (2009)

Background Reference 03

Neumann, E., Cancer Res. 58 (18), 4090-4095 (1998)

Other Product Names

Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma, PRAME, MAPE, OIP4

Tested Applications

WB, IHC-P, Flow

Protein ID

6685631

Physical Properties

Liquid

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