RRM2 Antibody
Product Specifications
Background
RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
NCBI Gene ID
6241
Swiss Prot
P31350
Accession Number
P31350
Host
Rabbit
Reactivity
Human
Immunogen
This RRM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human RRM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
RRM2
NCBI Official Name
Ribonucleoside-diphosphate reductase subunit M2
NCBI Organism
Homo sapiens
Background Reference 01
Kolesar, J., Cancer Chemother. Pharmacol. 64 (1), 79-86 (2009)
Background Reference 02
Liu, X., Methods Mol. Biol. 477, 195-206 (2008)
Other Product Names
Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, RRM2, RR2
Tested Applications
WB, IHC-P
Protein ID
400979
Physical Properties
Liquid
Curated Selection
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