CTSE Antibody
Product Specifications
Background
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.
NCBI Gene ID
1510
Swiss Prot
P14091
Accession Number
P14091
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CTSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human CTSE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
CTSE
NCBI Official Name
Cathepsin E
NCBI Organism
Homo sapiens
Background Reference 01
Caruso, M., Virchows Arch. 454 (3), 291-302 (2009)
Background Reference 02
Burster, T., Biochem. Biophys. Res. Commun. 377 (4), 1299-1303 (2008)
Other Product Names
Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE
Tested Applications
WB, IHC-P, Flow
Protein ID
46397366
Physical Properties
Liquid
Curated Selection
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