HFE Antibody
Product Specifications
Background
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M) . It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
NCBI Gene ID
3077
Swiss Prot
Q30201
Accession Number
Q30201
Host
Rabbit
Reactivity
Human
Immunogen
This HFE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human HFE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
HFE
NCBI Official Name
Hereditary hemochromatosis protein
NCBI Organism
Homo sapiens
Background Reference 01
Valenti, L., ClinAm Soc Nephrol (8), 1331-1337 (2009)
Background Reference 02
Won, J.E., Intervirology 52 (5), 239-246 (2009)
Other Product Names
Hereditary hemochromatosis protein, HLA-H, HFE, HLAH
Tested Applications
WB, IHC-P
Protein ID
2497915
Physical Properties
Liquid
Curated Selection
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