MAGEA12 Antibody

Product Specifications

Background

MAGEA12 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This gene is expressed in various tumors and tumor cell lines from different tissue origins, but not detected in normal tissues, except testis. The function of this gene is unknown. This and other MAGE genes form a gene cluster at chromosome Xq28 region.

NCBI Gene ID

4111

Swiss Prot

P43365

Accession Number

P43365

Host

Rabbit

Reactivity

Human

Immunogen

This MAGEA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

MAGEA12

NCBI Official Name

Melanoma-associated antigen 12

NCBI Organism

Homo sapiens

Background Reference 01

Mallon, A.M., et al., Genome Res. 10 (6) :758-775 (2000) .

Background Reference 02

Rogner, U.C., et al., Genomics 29 (3) :725-731 (1995) .

Background Reference 03

Ding, M., et al., Biochem. Biophys. Res. Commun. 202 (1) :549-555 (1994) .

Background Reference 04

De Smet, C., et al., Immunogenetics 39 (2) :121-129 (1994) .

Other Product Names

Melanoma-associated antigen 12, Cancer/testis antigen 112, CT112, MAGE-12 antigen, MAGE12F antigen, MAGEA12, MAGE12

Tested Applications

WB, IHC-P

Protein ID

14286145

Physical Properties

Liquid

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