VLDLR Antibody

Product Specifications

Background

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq].

NCBI Gene ID

7436

Swiss Prot

P98155

Accession Number

P98155

Host

Rabbit

Reactivity

Human

Immunogen

This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 amino acids from the Central region of human VLDLR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

96 kDa

Fragment

Rabbit Ig

Symbol

VLDLR

NCBI Official Name

Very low-density lipoprotein receptor

NCBI Organism

Homo sapiens

Background Reference 01

Sakai, K., et al. Brain Res. 1276, 11-21 (2009)

Background Reference 02

Francis, P.J., et al. J. Med. Genet. 46 (5) :300-307 (2009)

Background Reference 03

Ananyeva, N.M., et al. Blood Coagul. Fibrinolysis 19 (6) :543-555 (2008)

Background Reference 04

Turkmen, S., et al. Eur. J. Hum. Genet. 16 (9) :1070-1074 (2008)

Other Product Names

Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Tested Applications

WB, IHC-P, Flow

Protein ID

1730111

Physical Properties

Liquid

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