MCCC1 Antibody

Product Specifications

Background

MCCC1 is the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA.

NCBI Gene ID

56922

Swiss Prot

Q96RQ3

Accession Number

Q96RQ3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MCCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-425 amino acids from the Central region of human MCCC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MCCC1

NCBI Official Name

Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Holzinger, A., et al. Hum. Mol. Genet. 10 (12) :1299-1306 (2001)

Background Reference 02

Obata, K., et al. Genomics 72 (2) :145-152 (2001)

Background Reference 03

Baumgartner, M.R., et al. J. Clin. Invest. 107 (4) :495-504 (2001)

Background Reference 04

Gallardo, M.E., et al. Am. J. Hum. Genet. 68 (2) :334-346 (2001)

Other Product Names

Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha, MCCC1, MCCA