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MC2R Antibody

Product Specifications

Background

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC) . MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands.

NCBI Gene ID

4158

Swiss Prot

Q01718

Accession Number

Q01718

Host

Rabbit

Reactivity

Human

Immunogen

This MC2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the C-terminal region of human MC2R.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

MC2R

NCBI Official Name

Adrenocorticotropic hormone receptor

NCBI Organism

Homo sapiens

Background Reference 01

Holliday, K.L., et al. Ann. Rheum. Dis. 69 (3) :556-560 (2010)

Background Reference 02

Ding, Y.X., et al. Pharmacogenet. Genomics 20 (2) :71-76 (2010)

Background Reference 03

Roy, S., et al. Endocrinology 151 (2) :660-670 (2010)

Other Product Names

Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R, MC2R, ACTHR

Tested Applications

WB, IHC-P, Flow

Protein ID

399002

Physical Properties

Liquid

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