SIKE Antibody
Product Specifications
Background
SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]) .
NCBI Gene ID
80143
Swiss Prot
Q9BRV8
Accession Number
Q9BRV8
Host
Rabbit
Reactivity
Human
Immunogen
This SIKE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human SIKE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
SIKE1
NCBI Official Name
Suppressor of IKBKE 1
NCBI Organism
Homo sapiens
Background Reference 01
Goudreault, M., et al. Mol. Cell Proteomics 8 (1) :157-171 (2009)
Background Reference 02
Huang, J., et al. EMBO J. 24 (23) :4018-4028 (2005)
Other Product Names
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, SIKE1, SIKE
Tested Applications
WB, IHC-P
Protein ID
74752290
Physical Properties
Liquid
Curated Selection
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