G6PC Antibody
Product Specifications
Background
Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.
NCBI Gene ID
2538
Swiss Prot
P35575
Accession Number
P35575
Host
Rabbit
Reactivity
Human
Immunogen
This G6PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-149 amino acids from the Central region of human G6PC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
G6PC
NCBI Official Name
Glucose-6-phosphatase
NCBI Organism
Homo sapiens
Background Reference 01
Tu, E., et al. Hum. Pathol. 41 (3) :392-400 (2010)
Background Reference 02
Samuel, V.T., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (29) :12121-12126 (2009)
Background Reference 03
Hu, C., et al. Diabetologia 52 (3) :451-456 (2009)
Other Product Names
Glucose-6-phosphatase, G-6-Pase, G6Pase, Glucose-6-phosphatase alpha, G6Pase-alpha, G6PC, G6PT
Tested Applications
WB, IHC-P, Flow
Protein ID
206729864
Physical Properties
Liquid
Curated Selection
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