Roundabout 4 Antibody
Product Specifications
Background
Roundabout 4 is receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. This protein may mediate the inhibition of primary endothelial cell migration by Slit proteins.
NCBI Gene ID
54538
Swiss Prot
Q8WZ75
Accession Number
Q8WZ75
Host
Rabbit
Reactivity
Human
Immunogen
This Roundabout 4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the N-terminal region of human Roundabout 4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
107 kDa
Fragment
Rabbit Ig
Symbol
ROBO4
NCBI Official Name
Roundabout homolog 4
NCBI Organism
Homo sapiens
Background Reference 01
Jones, C.A., et al. Nat. Cell Biol. 11 (11) :1325-1331 (2009)
Background Reference 02
Sheldon, H., et al. FASEB J. 23 (2) :513-522 (2009)
Background Reference 03
Huang, L., et al. Mol. Vis. 15, 1057-1069 (2009)
Other Product Names
Roundabout homolog 4, Magic roundabout, ROBO4
Tested Applications
WB, IHC-P, Flow
Protein ID
49036490
Physical Properties
Liquid
Curated Selection
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