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PMPCB Antibody

Product Specifications

Background

PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.

NCBI Gene ID

9512

Swiss Prot

O75439

Accession Number

O75439

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PMPCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human PMPCB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

PMPCB

NCBI Official Name

Mitochondrial-processing peptidase subunit beta

NCBI Organism

Homo sapiens

Background Reference 01

Luczynski, W., et al. Neoplasma 56 (5) :428-434 (2009)

Background Reference 02

Schwer, B., et al. J. Cell Biol. 158 (4) :647-657 (2002)

Background Reference 03

Nagao, Y., et al. J. Biol. Chem. 275 (44) :34552-34556 (2000)

Other Product Names

Mitochondrial-processing peptidase subunit beta, Beta-MPP, P-52, PMPCB, MPPB

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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