PAN3 Antibody

Product Specifications

Background

PAN3 is functions in cytoplasmic mRNA decay. It is as part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity.

NCBI Gene ID

255967

Swiss Prot

Q58A45

Accession Number

Q58A45

Host

Rabbit

Reactivity

Human

Immunogen

This PAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-799 amino acids from the C-terminal region of human PAN3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

96 kDa

Fragment

Rabbit Ig

Symbol

PAN3

NCBI Official Name

PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}

NCBI Organism

Homo sapiens

Background Reference 01

Uchida, N., et al. J. Biol. Chem. 279 (2) :1383-1391 (2004)

Other Product Names

PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255|HAMAP-Rule:MF_03181}, hPan3, PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}