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PSG7 Antibody

Product Specifications

Background

PSG7 is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene.

NCBI Gene ID

5676

Swiss Prot

Q13046

Accession Number

Q13046

Host

Rabbit

Reactivity

Human

Immunogen

This PSG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-293 amino acids from the C-terminal region of human PSG7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Symbol

PSG7

NCBI Official Name

Putative pregnancy-specific beta-1-glycoprotein 7

NCBI Organism

Homo sapiens

Background Reference 01

Grimwood, J., et al. Nature 428 (6982) :529-535 (2004)

Background Reference 02

Beauchemin, N., et al. Exp. Cell Res. 252 (2) :243-249 (1999)

Background Reference 03

Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)

Other Product Names

Putative pregnancy-specific beta-1-glycoprotein 7, PS-beta-G-7, PSBG-7, Pregnancy-specific glycoprotein 7, PSG7

Tested Applications

WB, IHC-P, Flow

Protein ID

108935881

Physical Properties

Liquid

Curated Selection

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