APITD1 Antibody

Product Specifications

Background

APITD1 was identified in the neuroblastoma tumour suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumours, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway.

NCBI Gene ID

100526739378708

Swiss Prot

Q8N2Z9

Accession Number

Q8N2Z9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This APITD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human APITD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

APITD1

NCBI Official Name

Centromere protein S

NCBI Organism

Homo sapiens

Background Reference 01

Amano, M., et al. J. Cell Biol. 186 (2) :173-182 (2009)

Background Reference 02

Van Gils, W., et al. Invest. Ophthalmol. Vis. Sci. 48 (11) :4919-4923 (2007)

Background Reference 03

Okada, M., et al. Nat. Cell Biol. 8 (5) :446-457 (2006)

Other Product Names

Centromere protein S, CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa, APITD1, CENPS, FAAP16, MHF1