TSPAN7 Antibody
Product Specifications
Background
TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.
NCBI Gene ID
7102
Swiss Prot
P41732
Accession Number
P41732
Host
Rabbit
Reactivity
Human
Immunogen
This TSPAN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-124 amino acids from the Central region of human TSPAN7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
TSPAN7
NCBI Official Name
Tetraspanin-7
NCBI Organism
Homo sapiens
Background Reference 01
Radhakrishnan, Y., et al. Biol. Reprod. 81 (4) :647-656 (2009)
Background Reference 02
Guilmatre, A., et al. Arch. Gen. Psychiatry 66 (9) :947-956 (2009)
Background Reference 03
Noor, A., et al. Psychiatr. Genet. 19 (3) :154-155 (2009)
Other Product Names
Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD231, TSPAN7, A15, DXS1692E, MXS1, TM4SF2
Tested Applications
WB, Flow
Protein ID
17380550
Physical Properties
Liquid
Curated Selection
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