ATF1 Antibody

Product Specifications

Background

ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.

NCBI Gene ID

466

Swiss Prot

P18846

Accession Number

P18846

Host

Rabbit

Reactivity

Human

Immunogen

This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the C-terminal region of human ATF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Symbol

ATF1

NCBI Official Name

Cyclic AMP-dependent transcription factor ATF-1

NCBI Organism

Homo sapiens

Background Reference 01

Wang, W.L., et al. Mod. Pathol. 22 (9) :1201-1209 (2009)

Background Reference 02

Vega, A., et al. Gynecol. Oncol. 112 (1) :210-214 (2009)

Background Reference 03

Zheng, D., et al. Cancer Res. 68 (18) :7650-7660 (2008)

Other Product Names

Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36, ATF1

Tested Applications

WB, Flow

Protein ID

1168542

Physical Properties

Liquid

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